Comorbidities and Mortality in Bipolar Disorder

Bipolar disorder is associated with premature mortality, but the specific causes and underlying pathways are unclear.

To examine the physical health effects of bipolar disorder using outpatient and inpatient data for a national population. DESIGN, SETTING, AND PARTICIPANTS: National cohort study of 6,587,036 Swedish adults, including 6618 with bipolar disorder. MAIN OUTCOMES AND MEASURES: Physical comorbidities diagnosed in any outpatient or inpatient setting nationwide and mortality (January 1, 2003, through December 31, 2009).