Inflammatory proteins in plasma and the risk of dementia: the rotterdam study.

Engelhart, Marianne J.; Geerlings, Mirjam I.; Meijer, John; Kiliaan, Amanda J.; Ruitenberg, Annemieke; Swieten, John C. van; Stijnen, Theo; Hofman, Albert; Witteman, Jacqueline C.M.; Breteler, Monique M.B.

doi:10.1001/archneur.61.5.668

articlePubMedMay 1, 2004Closed access

Inflammatory proteins in plasma and the risk of dementia: the rotterdam study.

MJMarianne J. Engelhart MIMirjam I. Geerlings JMJohn Meijer AJAmanda J. Kiliaan ARAnnemieke Ruitenberg

Erasmus MC

PubMed

Indexed inpubmed

Abstract

Background

Increased levels of inflammatory proteins have been found in the brains and plasma samples of patients with dementia. Whether the levels of inflammatory proteins in plasma samples are elevated before clinical onset of dementia is unclear.

Objective

To determine whether high levels of inflammatory proteins in plasma samples are associated with an increased risk of dementia. DESIGN AND SETTING: A case-cohort study within the Rotterdam Study, a population-based prospective cohort study in the Netherlands.

Citation impact

746

total citations

FWCI: 10.81
Percentile: 100%
References: 27

Citations per year

Authors

10

Topics & keywords

Topics

Keywords

Dementia
Confidence interval
Rotterdam Study
Internal medicine
Medicine
C-reactive protein
Population
Prospective cohort study

UN Sustainable Development Goals

Good health and well-being

No related works found for this paper.