The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions
Centre National de la Recherche Scientifique · University of California, Los Angeles · +14 more institutions
Abstract
Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia), which were inherited from the common ancestor of plants and animals, but lost in land plants. We sequenced the approximately 120-megabase nuclear genome of Chlamydomonas and performed comparative phylogenomic analyses, identifying genes encoding uncharacterized proteins that are likely associated with the function and biogenesis of chloroplasts or eukaryotic flagella. Analyses of the Chlamydomonas genome advance our understanding of the ancestral…
Citation impact
- FWCI
- 52.47
- Percentile
- 100%
- References
- 54
Authors
117- SMSabeeha MerchantCorresponding
Centre National de la Recherche Scientifique, University of California, Los Angeles, University of Massachusetts Chan Medical School, Duke University, Joint Genome Institute, Sorbonne Université, Institut de Biologie Physico-Chimique
- SPSimon Prochnik
Centre National de la Recherche Scientifique, Los Alamos National Laboratory, University of California, Los Angeles, University of Massachusetts Chan Medical School, Duke University, Joint Genome Institute, Sorbonne Université, Institut de Biologie Physico-Chimique
- OVOlivier Vallon
Centre National de la Recherche Scientifique, University of California, Los Angeles, University of Massachusetts Chan Medical School, Duke University, Joint Genome Institute, Sorbonne Université, Institut de Biologie Physico-Chimique
- EHElizabeth H. Harris
Centre National de la Recherche Scientifique, University of California, Los Angeles, University of Massachusetts Chan Medical School, Duke University, Joint Genome Institute, Sorbonne Université, Institut de Biologie Physico-Chimique
- SJSteven J. Karpowicz
Centre National de la Recherche Scientifique, University of California, Los Angeles, University of Massachusetts Chan Medical School, Duke University, Joint Genome Institute, Sorbonne Université, Institut de Biologie Physico-Chimique
Topics & keywords
- Chlamydomonas
- Chlamydomonas reinhardtii
- Flagellum
- Biology
- Genome
- Chloroplast
- Biogenesis
- Lineage (genetic)
- Life in Land