articleMedChemCommJan 1, 2011Closed access

Minisci reactions: Versatile CH-functionalizations for medicinal chemists

Evotec (United States)

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Abstract

The addition of a radical to a heteroaromatic base is commonly referred to as a Minsici reaction. Such reactions constitute a broad-set of selective CH-functionalization processes. This review describes some of the major applications of Minisci reactions and related processes to medicinal or biological chemistry, and highlights some potential developments within this area.

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594
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Keywords
  • Chemistry
  • Combinatorial chemistry
  • Nanotechnology
  • Biochemical engineering
  • Engineering
  • Materials science
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