Is the ADHD brain wired differently? A review on structural and functional connectivity in attention deficit hyperactivity disorder

In recent years, a change in perspective in etiological models of attention deficit hyperactivity disorder (ADHD) has occurred in concordance with emerging concepts in other neuropsychiatric disorders such as schizophrenia and autism. These models shift the focus of the assumed pathology from regional brain abnormalities to dysfunction in distributed network organization. In the current contribution, we report findings from functional connectivity studies during resting and task states, as well as from studies on structural connectivity using diffusion tensor imaging, in subjects with ADHD. Although major methodological limitations in analyzing connectivity measures derived from noninvasive in vivo…

• BF
  Bundesministerium für Bildung und Forschung

  Awards: 01GJ0808, 01GV0602
• FM
  Federalno Ministarstvo Obrazovanja i Nauke
• NI
  National Institutes of Health

  Awards: MH074457, R01-MH074457, R01-MH074457-01A1, NIH R01