reviewChemical Society ReviewsJan 1, 2012Closed access

Cationic polymers and their therapeutic potential

Ghent University · Tufts University · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

The last decade has witnessed enormous research focused on cationic polymers. Cationic polymers are the subject of intense research as non-viral gene delivery systems, due to their flexible properties, facile synthesis, robustness and proven gene delivery efficiency. Here, we review the most recent scientific advances in cationic polymers and their derivatives not only for gene delivery purposes but also for various alternative therapeutic applications. An overview of the synthesis and preparation of cationic polymers is provided along with their inherent bioactive and intrinsic therapeutic potential. In addition, cationic polymer based biomedical materials are covered. Major progress in the fields of drug and…

Citation impact

698
total citations
FWCI
18.41
Percentile
100%
References
354
Citations per year

Authors

8

Topics & keywords

Keywords
  • Cationic polymerization
  • Gene delivery
  • Polymer
  • Drug delivery
  • Nanotechnology
  • Materials science
  • Chemistry
  • Genetic enhancement
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