Abstract
The Immune Epitope Database (IEDB, www.iedb.org) provides a catalog of experimentally characterized B and T cell epitopes, as well as data on Major Histocompatibility Complex (MHC) binding and MHC ligand elution experiments. The database represents the molecular structures recognized by adaptive immune receptors and the experimental contexts in which these molecules were determined to be immune epitopes. Epitopes recognized in humans, nonhuman primates, rodents, pigs, cats and all other tested species are included. Both positive and negative experimental results are captured. Over the course of 4 years, the data from 180,978 experiments were curated manually from the literature, which covers approximately 99%…
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Authors
9Topics & keywords
Topics
Keywords
- Epitope
- Biology
- Major histocompatibility complex
- Immune system
- Computational biology
- Database
- Antigen
- Genetics
UN Sustainable Development Goals
- Good health and well-being
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