reviewNew England Journal of MedicineJan 18, 2006Closed access

Estrogen Carcinogenesis in Breast Cancer

JDJames D. YagerNENancy E. Davidson

Johns Hopkins University · Public Health Department · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Estrogen exposure is a major determinant of the risk of breast cancer. This article reviews how genotoxic, mutagenic metabolites of estrogen and stimulation of tissue growth by the hormone participate in the pathogenesis of breast cancer.

Citation impact

1,864
total citations
FWCI
66.84
Percentile
100%
References
120
Citations per year

Authors

2

Topics & keywords

Topics
Keywords
  • Breast cancer
  • Estrogen
  • Medicine
  • Carcinogenesis
  • Pathogenesis
  • Hormone
  • Oncology
  • Cancer
UN Sustainable Development Goals
  • Good health and well-being
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