Muscles and their myokines

In the past, the role of physical activity as a life-style modulating factor has been considered as that of a tool to balance energy intake. Although it is important to avoid obesity, physical inactivity should be discussed in a much broader context. There is accumulating epidemiological evidence that a physically active life plays an independent role in the protection against type 2 diabetes, cardiovascular diseases, cancer, dementia and even depression. For most of the last century, researchers sought a link between muscle contraction and humoral changes in the form of an 'exercise factor', which could be released from skeletal muscle during contraction and mediate some of the exercise-induced metabolic…

• SF
  Strategiske Forskningsråd

  Awards: 09-067009 and 09-075724, 09-067009, 09-075724
• SO
  Sundhed og Sygdom, Det Frie Forskningsråd
• NR
  National Research Foundation
• DG
  Danmarks Grundforskningsfond

  Awards: 09-067009, 02-512-55, 09-075724
• MD
  Ministério da Ciência, Tecnologia e Inovação
• MR
  Medical Research Council