articleNew England Journal of MedicineMar 7, 2002BRONZE OA

The Risk of Major Birth Defects after Intracytoplasmic Sperm Injection and in Vitro Fertilization

The Kids Research Institute Australia · University of Western Australia · +2 more institutions

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Abstract

Background

It is not known whether infants conceived with use of intracytoplasmic sperm injection or in vitro fertilization have a higher risk of birth defects than infants conceived naturally.

Methods

We obtained data from three registries in Western Australia on births, births after assisted conception, and major birth defects in infants born between 1993 and 1997. We assessed the prevalence of major birth defects diagnosed by one year of age in infants conceived naturally or with use of intracytoplasmic sperm injection or in vitro fertilization.

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