The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates
Centre National de la Recherche Scientifique · Inserm · +15 more institutions
Abstract
Vertebrate evolution has been shaped by several rounds of whole-genome duplications (WGDs) that are often suggested to be associated with adaptive radiations and evolutionary innovations. Due to an additional round of WGD, the rainbow trout genome offers a unique opportunity to investigate the early evolutionary fate of a duplicated vertebrate genome. Here we show that after 100 million years of evolution the two ancestral subgenomes have remained extremely collinear, despite the loss of half of the duplicated protein-coding genes, mostly through pseudogenization. In striking contrast is the fate of miRNA genes that have almost all been retained as duplicated copies. The slow and stepwise rediploidization…
Citation impact
- FWCI
- 73.26
- Percentile
- 100%
- References
- 74
Authors
30- CBCamille BerthelotCorresponding
Centre National de la Recherche Scientifique, Inserm, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Genoscope, Institut de Biologie de l'École Normale Supérieure
- FBFrédéric Brunet
Université Claude Bernard Lyon 1, École Normale Supérieure de Lyon, Centre National de la Recherche Scientifique, Centre Max Weber, Institut de Génomique Fonctionnelle de Lyon
- DCDomitille Chalopin
Université Claude Bernard Lyon 1, École Normale Supérieure de Lyon, Centre National de la Recherche Scientifique, Centre Max Weber, Institut de Génomique Fonctionnelle de Lyon
- AJAmélie Juanchich
Laboratoire de Physiologie et Génomique des Poissons
- MBMaria Bernard
Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Genoscope, Génétique Animale et Biologie Intégrative
Topics & keywords
- Rainbow trout
- Gene duplication
- Genome
- Biology
- Evolutionary biology
- Trout
- Genome evolution
- Fish <Actinopterygii>