Macroscopic Evaluation of Rectal Cancer Resection Specimen: Clinical Significance of the Pathologist in Quality Control
Radboud University Nijmegen · Leiden University Medical Center · +2 more institutions
Abstract
Included were 180 patients. In 24% (n = 43), the mesorectum was incomplete. Patients in this group had an increased risk for local and distant recurrence, 36.1% v 20.3% recurrence in the group with a complete mesorectum (P = .02). Follow-up is too short to observe an effect on survival rates.
A patient’s prognosis is predicted by applying a classification of macroscopic completeness on a rectal resection specimen. We conclude that pathologists are able to judge the quality of TME for rectal cancer. With this direct interdisciplinary assessment instrument, we establish a new role of the pathologist in quality control.
Citation impact
- FWCI
- 9.30
- Percentile
- 100%
- References
- 14
Authors
6- IDIrıs D. NagtegaalCorresponding
Radboud University Nijmegen, Leiden University Medical Center, Radboud University Medical Center
- CJCornelis J.�H. van de Velde
University of Leeds, Radboud University Nijmegen, Leiden University Medical Center, Radboud University Medical Center
- EVErik van der Worp
University of Leeds, Radboud University Nijmegen, Leiden University Medical Center, Radboud University Medical Center
- EKEllen Kapiteijn
University of Leeds, Radboud University Nijmegen, Leiden University Medical Center, Radboud University Medical Center
- PQPhilip Quirke
University of Leeds, Radboud University Nijmegen, Leiden University Medical Center, Radboud University Medical Center
Topics & keywords
- Medicine
- Mesorectum
- Colorectal cancer
- Total mesorectal excision
- Randomized controlled trial
- Surgery
- Radiology
- Cancer