articleNucleic Acids ResearchNov 22, 2012GOLD OA

The Standard European Vector Architecture (SEVA): a coherent platform for the analysis and deployment of complex prokaryotic phenotypes

Centro Nacional de Biotecnología

PubMed
Indexed incrossrefdoajpubmed

Abstract

The 'Standard European Vector Architecture' database (SEVA-DB, http://seva.cnb.csic.es) was conceived as a user-friendly, web-based resource and a material clone repository to assist in the choice of optimal plasmid vectors for de-constructing and re-constructing complex prokaryotic phenotypes. The SEVA-DB adopts simple design concepts that facilitate the swapping of functional modules and the extension of genome engineering options to microorganisms beyond typical laboratory strains. Under the SEVA standard, every DNA portion of the plasmid vectors is minimized, edited for flaws in their sequence and/or functionality, and endowed with physical connectivity through three inter-segment insulators that are…

Citation impact

716
total citations
FWCI
10.75
Percentile
100%
References
80
Citations per year

Authors

12

Topics & keywords

Keywords
  • Biology
  • Plasmid
  • Computational biology
  • Vector (molecular biology)
  • Architecture
  • Genome
  • Computer science
  • Genetics
No related works found for this paper.

Funding