articleScienceSep 5, 2014GREEN OA

The coffee genome provides insight into the convergent evolution of caffeine biosynthesis

FDFrance DenœudLCLorenzo Carretero‐PauletADAlexis DereeperGDGaëtan DrocRGRomain Guyot

Centre National de la Recherche Scientifique · Commissariat à l'Énergie Atomique et aux Énergies Alternatives · +30 more institutions

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Abstract

Coffee is a valuable beverage crop due to its characteristic flavor, aroma, and the stimulating effects of caffeine. We generated a high-quality draft genome of the species Coffea canephora, which displays a conserved chromosomal gene order among asterid angiosperms. Although it shows no sign of the whole-genome triplication identified in Solanaceae species such as tomato, the genome includes several species-specific gene family expansions, among them N-methyltransferases (NMTs) involved in caffeine production, defense-related genes, and alkaloid and flavonoid enzymes involved in secondary compound synthesis. Comparative analyses of caffeine NMTs demonstrate that these genes expanded through sequential tandem…

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64

Topics & keywords

Topics
Keywords
  • Coffea
  • Coffea canephora
  • Genome
  • Caffeine
  • Biology
  • Gene
  • Coffea arabica
  • Evolutionary biology
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