Efficacy and Safety of Tadalafil Monotherapy for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia: A Meta-Analysis
Southeast University · Southeast University · +1 more institution
Indexed incrossrefpubmed
Abstract
Objective
To evaluate the efficacy and safety of tadalafil monotherapy for lower urinary tract symptoms secondary to benign prostatic hyperplasia (LUTS/BPH).
Methods
A comprehensive search was done to identify randomized controlled trials comparing the efficacy and safety of tadalafil for LUTS/BPH with placebos. Meta-analytical techniques were applied to evaluate the differences in the study results.
Results
Eight studies were identified and analyzed. Compared with placebo, tadalafil was associated with significant improvements in the International Prostate Symptom Score (IPSS) (mean difference = -2.19, p
Citation impact
4,542
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- FWCI
- 316.50
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Authors
6Topics & keywords
Topics
Keywords
- Tadalafil
- Medicine
- International Prostate Symptom Score
- Lower urinary tract symptoms
- Urology
- Erectile dysfunction
- Placebo
- Adverse effect
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