articleScienceDec 12, 2008Closed access

Developmental Patterning by Mechanical Signals in Arabidopsis

École Normale Supérieure de Lyon · California Institute of Technology · +8 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

A central question in developmental biology is whether and how mechanical forces serve as cues for cellular behavior and thereby regulate morphogenesis. We found that morphogenesis at the Arabidopsis shoot apex depends on the microtubule cytoskeleton, which in turn is regulated by mechanical stress. A combination of experiments and modeling shows that a feedback loop encompassing tissue morphology, stress patterns, and microtubule-mediated cellular properties is sufficient to account for the coordinated patterns of microtubule arrays observed in epidermal cells, as well as for patterns of apical morphogenesis.

Citation impact

947
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FWCI
60.44
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100%
References
45
Citations per year

Authors

12

Topics & keywords

Keywords
  • Morphogenesis
  • Microtubule
  • Arabidopsis
  • Cytoskeleton
  • Biology
  • Cell biology
  • Developmental biology
  • Genetics
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