Bismuth Sulfide Nanorods as a Precision Nanomedicine for in Vivo Multimodal Imaging-Guided Photothermal Therapy of Tumor
Institute of High Energy Physics · Chinese Academy of Sciences · +3 more institutions
Abstract
Here, we present a precision cancer nanomedicine based on Bi(2)S(3) nanorods (NRs) designed specifically for multispectral optoacoustic tomography (MSOT)/X-ray computed tomography (CT)-guided photothermal therapy (PTT). The as-prepared Bi(2)S(3) NRs possess ideal photothermal effect and contrast enhancement in MSOT/CT bimodal imaging. These features make them simultaneously act as "satellite" and "precision targeted weapon" for the visual guide to destruction of tumors in vivo, realizing effective tumor destruction and metastasis inhibition after intravenous injection. In addition, toxicity screening confirms that Bi(2)S(3) NRs have well biocompatibility. This triple-modality-nanoparticle approach enables…
Citation impact
- FWCI
- 42.91
- Percentile
- 100%
- References
- 73
Authors
12- JLJing LiuCorresponding
Institute of High Energy Physics, Chinese Academy of Sciences, National Center for Nanoscience and Technology
- XZXiaopeng Zheng
Institute of High Energy Physics, University of Chinese Academy of Sciences, Chinese Academy of Sciences, National Center for Nanoscience and Technology
- LYLiang Yan
National Center for Nanoscience and Technology, Chinese Academy of Sciences, Institute of High Energy Physics
- LZLiangjun Zhou
Chinese Academy of Sciences, National Center for Nanoscience and Technology, Institute of High Energy Physics, University of Chinese Academy of Sciences
- GTGan Tian
Institute of High Energy Physics, Chinese Academy of Sciences, National Center for Nanoscience and Technology
Topics & keywords
- Photothermal therapy
- Nanomedicine
- Cancer imaging
- In vivo
- Nanorod
- Biocompatibility
- Materials science
- Nanotechnology
- Good health and well-being