reviewCirculationAug 6, 2012BRONZE OA

The Assessment of Endothelial Function

Libin Cardiovascular Institute of Alberta · Great Ormond Street Hospital · +11 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

The discovery of the endothelium as a crucial organ for the regulation of the vasculature to physiological needs and the recognition of endothelial dysfunction as a key pathological condition - which is associated with most if not all cardiovascular risk factors - led to a tremendous boost of endothelial research in the past 3 decades. Despite the possibility to measure endothelial function in the individual and its widespread use in research, its use as a clinical tool in daily medicine is not established yet. We review the most common methods to assess vascular function in humans and discuss their advantages and disadvantages. Furthermore we give an overview about clinical settings were endothelial function…

Citation impact

1,132
total citations
FWCI
40.39
Percentile
100%
References
199
Citations per year

Authors

12

Topics & keywords

Keywords
  • Medicine
  • Function (biology)
  • Intensive care medicine
  • Cell biology
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