reviewBloodFeb 7, 2011BRONZE OA

The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications

Consorci Institut D'Investigacions Biomediques August Pi I Sunyer · Universitat de Barcelona · +6 more institutions

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Abstract

The World Health Organization classification of lymphoid neoplasms updated in 2008 represents a worldwide consensus on the diagnosis of these tumors and is based on the recognition of distinct diseases, using a multidisciplinary approach. The updated classification refined the definitions of well-recognized diseases, identified new entities and variants, and incorporated emerging concepts in the understanding of lymphoid neoplasms. However, some questions were unresolved, such as the extent to which specific genetic or molecular alterations define certain tumors, and the status of provisional entities, categories for which the World Health Organization working groups felt there was insufficient evidence to…

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