articleAnnals of SurgeryAug 20, 2007GREEN OA

Extent of Surgery Affects Survival for Papillary Thyroid Cancer

Northwestern University · American College of Surgeons · +2 more institutions

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Abstract

Methods

From the National Cancer Data Base (1985–1998), 52,173 patients underwent surgery for PTC. Survival was estimated by the Kaplan-Meier method and compared using log-rank tests. Cox Proportional Hazards modeling stratified by tumor size was used to assess the impact of surgical extent on outcomes and to identify a tumor size threshold above which total thyroidectomy is associated with an improvement in recurrence and long-term survival rates.

Results

Of the 52,173 patients, 43,227 (82.9%) underwent total thyroidectomy, and 8946 (17.1%) underwent lobectomy. For PTC

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Funding