Resting-state networks link invasive and noninvasive brain stimulation across diverse psychiatric and neurological diseases
Beth Israel Deaconess Medical Center · Harvard University · +8 more institutions
Abstract
Brain stimulation, a therapy increasingly used for neurological and psychiatric disease, traditionally is divided into invasive approaches, such as deep brain stimulation (DBS), and noninvasive approaches, such as transcranial magnetic stimulation. The relationship between these approaches is unknown, therapeutic mechanisms remain unclear, and the ideal stimulation site for a given technique is often ambiguous, limiting optimization of the stimulation and its application in further disorders. In this article, we identify diseases treated with both types of stimulation, list the stimulation sites thought to be most effective in each disease, and test the hypothesis that these sites are different nodes within…
Citation impact
- FWCI
- 23.52
- Percentile
- 100%
- References
- 226
Authors
6- MFMichael FoxCorresponding
Beth Israel Deaconess Medical Center, Harvard University, Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Berenson Allen Center for Noninvasive Brain Stimulation
- RLRandy L. Buckner
Harvard University, Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging
- HLHesheng Liu
Harvard University, Athinoula A. Martinos Center for Biomedical Imaging
- MMM. Mallar Chakravarty
Douglas Mental Health University Institute, McGill University
- AMAndrés M. Lozano
University of Toronto, Toronto Western Hospital, Krembil Foundation
Topics & keywords
- Brain stimulation
- Stimulation
- Neuroscience
- Deep brain stimulation
- Resting state fMRI
- Brain disease
- Disease
- Medicine
- Good health and well-being
Funding
- MJMichael J. Fox Foundation for Parkinson's Research
- ABAmerican Brain Foundation
- AAAmerican Academy of Neurology
- HCHarvard CatalystAwards: RR025758, UL1 RR025758
- NFNational Football League Players Association
- NINational Institutes of HealthAwards: K23NS083741, R21HD07616, R01HD069776, R21MH099196, R21NS082870, R21NS085491, UL1 RR025758, R01NS073601