Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Burton, Paul R.; Tobin, Martin D.; Burton, Paul R; Thompson, John R.; Burton, Paul R; Clayton, David; Stevens, H. E.; Downes, Kate; Clayton, David G; Dunger, David B; Nutland, Sarah; Clayton, David G; Leung, H.T.; Widmer, Barry; Todd, John A.; Walker, Neil; Morris, Andrew P.; Evans, David M.; Elliott, Kate; Cardon, Lon R; Zeggini, Eleftheria; Lyons, Emily; Teo, Yik Ying; Barrett, Jeffrey C.; Kwiatkowski, Dominic P; Kwiatkowski, Dominic P; Timpson, Nicolas J; McCarthy, Mark I; Rayner, Nigel W; Vannberg, Fredrik; Hill, Adrian V. S.; Lindgren, Cecilia M.; Rockett, Kirk A.; Cardon, Lon R; Craddock, Nick; Withers, David; Ghori, Mohammed J. R.; Deloukas, Panos; Keniry, Andrew; Ravindrarajah, Rathi; Chaney, Amy; Widden, Claire; Deloukas, Panos; Kwiatkowski, Dominic P; Keniry, Andrew; Attwood, Antony P; McGinnis, Ralph; Downes, Kate; Potter, Simon; Bumpstead, Suzannah J.; Deloukas, Panos; Hunt, Sarah; Gwilliam, Rhian; King, Emma; McGinnis, Ralph; Inouye, Michael; Whittaker, Pamela; Bentley, David; Duncanson, Audrey; McCarthy, Mark I.; Elliott, Kate; Zeggini, Eleftheria; Groves, Christopher J.; Rayner, Nigel W; McCarthy, Mark I.; McCarthy, Mark I; Lindgren, Cecilia M.; Boorman, James P; Taylor, Niall; Koch, Kerstin; Ouwehand, Willem H; Watkins, Nicholas A.; Winzer, Thilo; Ouwehand, Willem H; Attwood, Antony P; Jolley, Jennifer D.; Ouwehand, Willem H; Cant, Barbara; Knight, Alexandra S.; Boorman, James P; Ouwehand, Willem H; Watkins, Nicholas A.; Ouwehand, Willem H; Ouwehand, Willem H; Samani, Nilesh J; Dixon, Richard J.; Samani, Nilesh J.; Mangino, Massimo; Samani, Nilesh J; Stevens, Suzanne; Braund, Peter S.; Donnelly, Peter; Cardin, Niall J.; Spencer, Chris C. A.; Vukcevic, Damjan; Marchini, Jonathan; Pereira-Gale, Joanne; Davison, Dan; Hallgrimsdóttir, Ingeleif B; Teo, Yik Ying; Howie, Bryan; Ferreira, Teresa; Su, Zhan; Donnelly, Peter; Easton, Doug; Easton, Doug; Everson, Ursula; Hussey, Judith M.; Meech, Elizabeth; Prowse, C V; Walters, Graham R.; Pembrey, Marcus; McArdle, Wendy L.; Jones, Richard W.; Pembrey, Marcus; Ring, Susan M.; Strachan, David P.; Pembrey, Marcus; Pembrey, Marcus; Breen, Gerome; Clair, David St; Caesar, Sian; Gordon-Smith, Katharine; Jones, Lisa; Jones, Ian; Green, Elaine; Moskivina, Valentina; Craddock, Nick; Owen, Michael J.; Nikolov, Ivan; Craddock, Nick; Hamshere, Marian L.; Grozeva, Detelina; Fraser, Christine; O‘Donovan, Michael; Kirov, George; Holmans, Peter; Gordon-Smith, Katharine; Collier, David; McGuffin, Peter; Elkin, Amanda; Williamson, Richard; Farmer, Anne; Ferrier, I. Nicol; Young, Allan H.; Iles, Mark M.; Maqbool, Azhar; Bishop, D. Timothy; Balmforth, Anthony J.; Yuldasheva, Nadira; Hall, Alistair S.; Ball, Stephen G.; Barrett, Jennifer H.; Hall, Alistair S.; Tremelling, Mark; Bredin, Francesca; Parkes, Miles; Parkes, Miles; Nimmo, Elaine R.; Drummond, Hazel E.; Lees, Charles W; Satsangi, Jack; Matthew, Christopher G; Prescott, Natalie J.; Lewis, Cathryn M.; Onnie, Clive M.; Matthew, Christopher G; Fisher, Sheila; Forbes, Alastair; Sanderson, Jeremy; Mansfield, John; Mohiuddin, Mohamed Khalid; Barbour, Jamie; Todhunter, Catherine E; Cummings, Fraser; Ahmad, Tariq; Jewell, Derek P.; Webster, John; Brown, Morris J; Lathrop, Mark G.; Connell, John; Dominiczak, Anna F.; Caulfield, Mark; Dobson, Richard; Burke, Beverley; Caulfield, Mark; Marcano, C; Xue, Mingzhan; Munroe, Patricia B.; Gungadoo, Johannie; Lee, Kate; Wallace, Chris; Onipinla, Abiodun; Newhouse, Stephen; Farrall, Martin; Farrall, Martin; Symmons, Deborah; Bruce, Ian N; John, Sally; Potter, Catherine; Hinks, Anne; Barton, Anne; Worthington, Jane; Hilder, Samantha L; Donovan, Hannah; Worthington, Jane; Thomson, Wendy; Gilbert, Paul; Eyre, Steve; Silman, Alan J.; Widmer, Barry; Dunger, David B; Weedon, Michael N; Hattersley, Andrew T; Freathy, Rachel M; Hattersley, Andrew T; Lango, Hana; Perry, John R B; Frayling, Timothy M; Weedon, Michael N; Hattersley, Andrew T; Freathy, Rachel M; Shields, Beverley M.; Hattersley, Andrew T; Lango, Hana; Perry, John R B; Frayling, Timothy M; Hitman, G. A.; Walker, Mark; Timpson, Nicolas J; Sirugo, Giorgio; Conway, David J.; Newport, Melanie J.; Newport, Melanie J.; Jallow, Muminatou; Brown, Matthew A; Bradbury, Linda A; Brown, Matthew A; Wordsworth, Paul; Pointon, Jennifer J.; Brown, Matthew A; Brown, Matthew A.; Farrar, Claire; Newby, Paul; Carr‐Smith, Jackie; Brand, Stephan; Gough, Stephen CL; Gough, Stephen C L; Simmonds, Matthew J.; Heward, J. M.; Franklyn, Jayne A.; Mitchell, Sarah L; Rahman, Nazneen; Seal, Sheila; Rahman, Nazneen; Stratton, Michael R.; Stratton, Michael R; Stratton, Michael R.; Sawcer, Stephen; Goris, An; Compston, Alastair; Compston, Alastair; Ban, Maria; Bentley, David; Cardon, Lon R.; Cardon, Lon R; Cardon, Lon R; Pearce, Simon H. S.; Reveille, John D.; Zhou, Xiaodong; Bradbury, Linda A; Taylor, Jacqueline; Dowling, Alison; Sims, Anne-Marie; Brown, Matthew A; Doan, Tracy; Cardon, Lon R.; Davis, John C.; Brown, Matthew A; Wordsworth, Paul; Pointon, Jennifer J.; Savage, Laurie; Ward, Michael M.; Learch, Thomas L; Weisman, Michael H.

doi:10.1038/ng.2007.17

articleNature GeneticsOct 21, 2007GREEN OA

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

PRPaul R. Burton MDMartin D. TobinPR Paul R Burton JRJohn R. ThompsonPR Paul R Burton

University of Leicester · Juvenile Diabetes Research Foundation · +49 more institutions

PubMed

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Abstract

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1,374

total citations

FWCI: 68.36
Percentile: 100%
References: 51

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Authors

285

PR
Paul R. BurtonCorresponding
University of Leicester
MD
Martin D. Tobin
University of Leicester
PR
Paul R Burton
University of Leicester
JR
John R. Thompson
University of Leicester
PR
Paul R Burton
University of Leicester

Topics & keywords

Topics

Keywords

Single-nucleotide polymorphism
Ankylosing spondylitis
Biology
Nonsynonymous substitution
Major histocompatibility complex
Immunology
Autoimmunity
Case-control study

UN Sustainable Development Goals

Good health and well-being

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