PEGylated WS 2 Nanosheets as a Multifunctional Theranostic Agent for in vivo Dual‐Modal CT/Photoacoustic Imaging Guided Photothermal Therapy

A new generation of photothermal theranostic agents is developed based on PEGylated WS2 nanosheets. Bimodal in vivo CT/photoacoustic imaging reveals strong tumor contrast after either intratumoral or intravenous injection of WS2 -PEG. In vivo photothermal treatment is then conducted in a mouse tumor model, achieving excellent therapeutic efficacy with complete ablation of tumors. This work promises further exploration of transition-metal dichalcogenides for biomedical applications, such as cancer imaging and therapy.

• NN
  National Natural Science Foundation of China
• SU
  Soochow University