The severity of acute kidney injury predicts progression to chronic kidney disease
Washington University Medical Center · George Washington University · +5 more institutions
Abstract
Acute kidney injury (AKI) is associated with progression to advanced chronic kidney disease (CKD). We tested whether patients who survive AKI and are at higher risk for CKD progression can be identified during their hospital admission, thus providing opportunities to intervene. This was assessed in patients in the Department of Veterans Affairs Healthcare System hospitalized with a primary diagnosis indicating AKI (ICD9 codes 584.xx). In the exploratory phase, three multivariate prediction models for progression to stage 4 CKD were developed. In the confirmatory phase, the models were validated in 11,589 patients admitted for myocardial infarction or pneumonia during the same time frame that had RIFLE codes R,…
Citation impact
- FWCI
- 23.33
- Percentile
- 100%
- References
- 26
Authors
5- LSLakhmir S. ChawlaCorresponding
Washington University Medical Center, George Washington University
- RARichard Amdur
Georgetown University, Veterans Health Administration
- SASusan Amodeo
Program Support Center, Veterans Health Administration
- PLPaul L. Kimmel
National Institute of Diabetes and Digestive and Kidney Diseases, George Washington University, National Institutes of Health, Washington University Medical Center
- CECarlos E. Palant
George Washington University, Veterans Health Administration, Washington University Medical Center
Topics & keywords
- Medicine
- Kidney disease
- Rifle
- Acute kidney injury
- Internal medicine
- Veterans Affairs
- Dialysis
- Renal function
- Good health and well-being