Plasmonic Copper Sulfide Nanocrystals Exhibiting Near-Infrared Photothermal and Photodynamic Therapeutic Effects
Chinese Academy of Sciences · Technical Institute of Physics and Chemistry · +4 more institutions
Abstract
Recently, plasmonic copper sulfide (Cu2-xS) nanocrystals (NCs) have attracted much attention as materials for photothermal therapy (PTT). Previous reports have correlated photoinduced cell death to the photothermal heat mechanism of these NCs, and no evidence of their photodynamic properties has been reported yet. Herein we have prepared physiologically stable near-infrared (NIR) plasmonic copper sulfide NCs and analyzed their photothermal and photodynamic properties, including therapeutic potential in cultured melanoma cells and a murine melanoma model. Interestingly, we observe that, besides a high PTT efficacy, these copper sulfide NCs additionally possess intrinsic NIR induced photodynamic activity,…
Citation impact
- FWCI
- 41.82
- Percentile
- 100%
- References
- 60
Authors
16- SWShunhao WangCorresponding
Chinese Academy of Sciences, Technical Institute of Physics and Chemistry, University of Chinese Academy of Sciences
- ARAndreas Riedinger
ETH Zurich, Italian Institute of Technology
- HLHongbo Li
Italian Institute of Technology
- CFChanghui Fu
Chinese Academy of Sciences, Technical Institute of Physics and Chemistry
- HLHuiyu Liu
Chinese Academy of Sciences, Technical Institute of Physics and Chemistry
Topics & keywords
- Photothermal therapy
- Materials science
- Plasmon
- Copper
- Copper sulfide
- Nanocrystal
- Photothermal effect
- Infrared