Stent Thrombosis in Randomized Clinical Trials of Drug-Eluting Stents
Baim Institute for Clinical Research · Brigham and Women's Hospital · +2 more institutions
Abstract
Definitions of stent thrombosis that have been used in clinical trials of drug-eluting stents have been restrictive and have not been used in a uniform manner.
We applied a hierarchical classification of stent thrombosis set by the Academic Research Consortium (ARC) across randomized trials involving 878 patients treated with sirolimus-eluting stents, 1400 treated with paclitaxel-eluting stents, and 2267 treated with bare-metal stents. We then pooled 4 years of follow-up data. All events were adjudicated by an independent clinical-events committee.
Citation impact
- FWCI
- 168.24
- Percentile
- 100%
- References
- 30
Authors
6- LMLaura MauriCorresponding
Baim Institute for Clinical Research, Brigham and Women's Hospital, Harvard University
- WHWen-Hua Hsieh
Baim Institute for Clinical Research
- JMJoseph M. Massaro
Baim Institute for Clinical Research
- KKKalon K.L. Ho
Hadassah Medical Center, Baim Institute for Clinical Research, Harvard University
- RBRalph B. D’Agostino
Baim Institute for Clinical Research
Topics & keywords
- Medicine
- Stent
- Sirolimus
- Randomized controlled trial
- Surgery
- Thrombosis
- Bare-metal stent
- Drug-eluting stent