Cystatin C and the Risk of Death and Cardiovascular Events among Elderly Persons
San Francisco VA Medical Center · University of Pittsburgh · +7 more institutions
Abstract
Cystatin C is a serum measure of renal function that appears to be independent of age, sex, and lean muscle mass. We compared creatinine and cystatin C levels as predictors of mortality from cardiovascular causes and from all causes in the Cardiovascular Health Study, a cohort study of elderly persons living in the community.
Creatinine and cystatin C were measured in serum samples collected from 4637 participants at the study visit in 1992 or 1993; follow-up continued until June 30, 2001. For each measure, the study population was divided into quintiles, with the fifth quintile subdivided into thirds (designated 5a, 5b, and 5c).
Citation impact
- FWCI
- 31.57
- Percentile
- 100%
- References
- 28
Authors
8- MGMichael G. ShlipakCorresponding
San Francisco VA Medical Center, University of Pittsburgh, University of California, San Francisco
- MJMark J. Sarnak
University of Pittsburgh, Tufts Medical Center
- RKRonit Katz
University of Pittsburgh, The Coordinating Center
- LFLinda F. Fried
University of Pittsburgh, VA Pittsburgh Healthcare System
- SLStephen L. Seliger
University of Pittsburgh, University of Maryland, Baltimore
Topics & keywords
- Medicine
- Cystatin C
- Hazard ratio
- Creatinine
- Renal function
- Confidence interval
- Internal medicine
- Liter
- Good health and well-being