Nanomaterial Toxicity Testing in the 21st Century: Use of a Predictive Toxicological Approach and High-Throughput Screening
California NanoSystems Institute · University of California, Los Angeles
Abstract
The production of engineered nanomaterials (ENMs) is a scientific breakthrough in material design and the development of new consumer products. While the successful implementation of nanotechnology is important for the growth of the global economy, we also need to consider the possible environmental health and safety (EHS) impact as a result of the novel physicochemical properties that could generate hazardous biological outcomes. In order to assess ENM hazard, reliable and reproducible screening approaches are needed to test the basic materials as well as nanoenabled products. A platform is required to investigate the potentially endless number of biophysicochemical interactions at the nano/bio interface, in…
Citation impact
- FWCI
- 21.59
- Percentile
- 100%
- References
- 19
Authors
7- AEAndré E. NelCorresponding
California NanoSystems Institute, University of California, Los Angeles
- TXTian Xia
California NanoSystems Institute, University of California, Los Angeles
- HMHuan Meng
California NanoSystems Institute, University of California, Los Angeles
- XWXiang Wang
University of California, Los Angeles, California NanoSystems Institute
- SLSijie Lin
California NanoSystems Institute, University of California, Los Angeles
Topics & keywords
- Hazard
- Test strategy
- Computer science
- Biochemical engineering
- Throughput
- High-throughput screening
- Risk assessment
- Risk analysis (engineering)