Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease
Mental Health Research Institute · The University of Melbourne · +6 more institutions
Abstract
Assess Aβ deposition longitudinally and explore its relationship with cognition and disease progression.
Clinical follow-up was obtained 20 ± 3 months after [¹¹C]Pittsburgh compound B (PiB)-positron emission tomography in 206 subjects: 35 with dementia of the Alzheimer type (DAT), 65 with mild cognitive impairment (MCI), and 106 age-matched healthy controls (HCs). A second PiB scan was obtained at follow-up in 185 subjects and a third scan after 3 years in 57.
Citation impact
- FWCI
- 46.42
- Percentile
- 100%
- References
- 42
Authors
17- VLVictor L. VillemagneCorresponding
Mental Health Research Institute, The University of Melbourne, Austin Health
- KEKerryn E. Pike
Mental Health Research Institute, The University of Melbourne, Austin Health
- GCGaël Chételat
Austin Health
- KAKathryn A. Ellis
The University of Melbourne, Health Sciences and Nutrition
- RSRachel S. Mulligan
Austin Health
Topics & keywords
- Pittsburgh compound B
- Dementia
- Internal medicine
- Psychology
- Alzheimer's disease
- Apolipoprotein E
- Cognitive decline
- Cognition