Near-Infrared Fluorescence Microscopy of Single-Walled Carbon Nanotubes in Phagocytic Cells
Rice University · Center for Nanoscale Science and Technology
Abstract
The uptake of pristine single-walled carbon nanotubes into macrophage-like cells has been studied using the nanotubes' intrinsic near-infrared fluorescence. Macrophage samples that have been incubated in growth media containing suspended single-walled nanotubes show characteristic nanotube fluorescence spectra. The fluorescence intensities increase smoothly with incubation time and external nanotube concentration. Near-infrared fluorescence microscopy at wavelengths above 1100 nm provides high contrast images indicating localization of nanotubes in numerous intracellular vesicles. Nanotube uptake appears to occur through phagocytosis. Population growth of macrophage cultures is unaffected by exposure to…
Citation impact
- FWCI
- 21.71
- Percentile
- 100%
- References
- 12
Authors
4- PCPaul CherukuriCorresponding
Rice University, Center for Nanoscale Science and Technology
- SMSergei M. Bachilo
Center for Nanoscale Science and Technology, Rice University
- SLSilvio Litovsky
Center for Nanoscale Science and Technology, Rice University
- RBR. Bruce Weisman
Rice University, Center for Nanoscale Science and Technology
Topics & keywords
- Carbon nanotube
- Chemistry
- Fluorescence
- Fluorescence microscope
- Biophysics
- Nanotube
- Microscopy
- Population