articleAdvanced Synthesis & CatalysisFeb 22, 2013GREEN OA

Recent Advances in Asymmetric Organocatalytic Construction of 3,3′‐Spirocyclic Oxindoles

LHLiang HongRWRui Wang

State Key Laboratory of Applied Organic Chemistry · Lanzhou University · +1 more institution

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Abstract

Abstract The asymmetric organocatalysis is definitely one of the most powerful and versatile tools for the rapid construction of various spirocyclic oxindoles. In the past few years, a number of successful strategies based on organocatalysis have been developed for the construction of 3,3′‐spirocyclic oxindoles in high yields and excellent enantioselectivities under mild conditions. In this review, recent advances in this area are summarized and classified according to the spiro ring fused at the 3‐position of the oxindole core.

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Topics & keywords

Topics
Keywords
  • Oxindole
  • Organocatalysis
  • Chemistry
  • Enantioselective synthesis
  • Ring (chemistry)
  • Combinatorial chemistry
  • Catalysis
  • Organic chemistry
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