InnateDB: systems biology of innate immunity and beyond—recent updates and continuing curation
Simon Fraser University · Teagasc - The Irish Agriculture and Food Development Authority · +1 more institution
Abstract
InnateDB (http://www.innatedb.com) is an integrated analysis platform that has been specifically designed to facilitate systems-level analyses of mammalian innate immunity networks, pathways and genes. In this article, we provide details of recent updates and improvements to the database. InnateDB now contains >196 000 human, mouse and bovine experimentally validated molecular interactions and 3000 pathway annotations of relevance to all mammalian cellular systems (i.e. not just immune relevant pathways and interactions). In addition, the InnateDB team has, to date, manually curated in excess of 18 000 molecular interactions of relevance to innate immunity, providing unprecedented insight into innate immunity…
Citation impact
- FWCI
- 10.14
- Percentile
- 100%
- References
- 24
Authors
10- KBKarin BreuerCorresponding
- AFAmir Foroushani
Simon Fraser University, Teagasc - The Irish Agriculture and Food Development Authority, University of British Columbia
- MRMatthew R. Laird
University of British Columbia, Simon Fraser University
- CCCarol Chen
Simon Fraser University, University of British Columbia
- ASAnastasia Sribnaia
University of British Columbia, Simon Fraser University
Topics & keywords
- Innate immune system
- Biology
- Computational biology
- Data curation
- Relevance (law)
- Ontology
- Immunity
- World Wide Web
- Zero hunger