The Global Circulation of Seasonal Influenza A (H3N2) Viruses
Centers for Disease Control and Prevention · Universitat Pompeu Fabra · +4 more institutions
Abstract
Antigenic and genetic analysis of the hemagglutinin of approximately 13,000 human influenza A (H3N2) viruses from six continents during 2002-2007 revealed that there was continuous circulation in east and Southeast Asia (E-SE Asia) via a region-wide network of temporally overlapping epidemics and that epidemics in the temperate regions were seeded from this network each year. Seed strains generally first reached Oceania, North America, and Europe, and later South America. This evidence suggests that once A (H3N2) viruses leave E-SE Asia, they are unlikely to contribute to long-term viral evolution. If the trends observed during this period are an accurate representation of overall patterns of spread, then the…
Citation impact
- FWCI
- 47.19
- Percentile
- 100%
- References
- 35
Authors
28- CAColin A. Russell
Centers for Disease Control and Prevention, Universitat Pompeu Fabra, University of Cambridge, Victorian Infectious Diseases Reference Laboratory, Erasmus University Rotterdam
- TCTerry C. Jones
Centers for Disease Control and Prevention, Universitat Pompeu Fabra, University of Cambridge, Victorian Infectious Diseases Reference Laboratory, Erasmus University Rotterdam
- IBIan Barr
Centers for Disease Control and Prevention, Universitat Pompeu Fabra, University of Cambridge, Victorian Infectious Diseases Reference Laboratory, Erasmus University Rotterdam
- NJNancy J. Cox
Centers for Disease Control and Prevention, Universitat Pompeu Fabra, University of Cambridge, Victorian Infectious Diseases Reference Laboratory, Erasmus University Rotterdam
- RGRebecca Garten
Centers for Disease Control and Prevention, Universitat Pompeu Fabra, University of Cambridge, Victorian Infectious Diseases Reference Laboratory, Erasmus University Rotterdam
Topics & keywords
- Hemagglutinin (influenza)
- East Asia
- Pandemic
- Circulation (fluid dynamics)
- Virology
- Geography
- Biology
- Strain (injury)
- Good health and well-being