Toward a mathematical theory of Keller–Segel models of pattern formation in biological tissues

This paper proposes a survey and critical analysis focused on a variety of chemotaxis models in biology, namely the classical Keller–Segel model and its subsequent modifications, which, in several cases, have been developed to obtain models that prevent the non-physical blow up of solutions. The presentation is organized in three parts. The first part focuses on a survey of some sample models, namely the original model and some of its developments, such as flux limited models, or models derived according to similar concepts. The second part is devoted to the qualitative analysis of analytic problems, such as the existence of solutions, blow-up and asymptotic behavior. The third part deals with the derivation…