The Global Burden of Disease Study 2010: Interpretation and Implications for the Neglected Tropical Diseases
Texas Children's Hospital · Rice University · +22 more institutions
Abstract
Cutaneous leishmaniasis is a neglected tropical disease, broadly distributed in the planet and with high incidence among socially vulnerable persons. It has been underestimated by healthcare systems and society, with a great burden of disease. Despite an available effective and well established treatment since the 50’s, it has been documented an increasing rate of resistance and treatment failure. Reports in Latin America, show resistance rates between 10-20% and 25% of subjects with treatment failure using first line drugs. Nevertheless, there is no clear association between reduced in vitro susceptibility from the parasite and treatment response. \n \nThis case control study with 34 subjects in a…
Citation impact
- FWCI
- 63.41
- Percentile
- 100%
- References
- 82
Authors
34- PJPeter J. HotezCorresponding
Texas Children's Hospital, Rice University, Sabin Vaccine Institute, Baylor College of Medicine
- MAMiriam Alvarado
University of Washington, Institute for Health Metrics and Evaluation
- MBMaría‐Gloria Basáñez
Imperial College London
- IBIan Bolliger
Institute for Health Metrics and Evaluation, University of Washington
- RBRupert Bourne
Anglia Ruskin University
Topics & keywords
- Neglected tropical diseases
- Tropical disease
- Burden of disease
- Disease burden
- Global health
- Tropical medicine
- Medicine
- Interpretation (philosophy)