Volume Progression in Polycystic Kidney Disease
University of Kansas Medical Center · Mayo Clinic · +5 more institutions
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Abstract
Background
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive enlargement of cyst-filled kidneys.
Methods
In a three-year study, we measured the rates of change in total kidney volume, total cyst volume, and iothalamate clearance in patients with ADPKD. Of a total of 241 patients, in 232 patients without azotemia who were 15 to 46 years old at baseline we used magnetic-resonance imaging to correlate the total kidney volume and total cyst volume with iothalamate clearance. Statistical methods included analysis of variance, Pearson correlation, and multivariate regression analysis.
Citation impact
787
total citations
- FWCI
- 18.90
- Percentile
- 100%
- References
- 28
Citations per year
Authors
17Topics & keywords
Topics
Keywords
- Medicine
- Polycystic kidney disease
- Polycystic disease
- Polycystic kidney
- Volume (thermodynamics)
- Kidney
- Urology
- Internal medicine
UN Sustainable Development Goals
- Good health and well-being
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