Effects of Testosterone on Muscle Strength, Physical Function, Body Composition, and Quality of Life in Intermediate-Frail and Frail Elderly Men: A Randomized, Double-Blind, Placebo-Controlled Study

University of Manchester · University of Auckland · +1 more institution

PubMed
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Abstract

Objective

Our objective was to determine the effects of 6 months T treatment in intermediate-frail and frail elderly men, on muscle mass and strength, physical function, and quality of life. DESIGN AND SETTING: We conducted a randomized, double-blind, placebo-controlled, parallel-group, single-center study.

Participants

PARTICIPANTS were community-dwelling intermediate-frail and frail elderly men at least 65 yr of age with a total T at or below 12 nmol/liter or free T at or below 250 pmol/liter.

Citation impact

623
total citations
FWCI
30.49
Percentile
100%
References
57
Citations per year

Authors

7

Topics & keywords

Keywords
  • Placebo
  • Lean body mass
  • Medicine
  • Isometric exercise
  • Randomized controlled trial
  • Internal medicine
  • Quality of life (healthcare)
  • Confidence interval
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Funding