Rotating Night Shift Work and Risk of Type 2 Diabetes: Two Prospective Cohort Studies in Women
Harvard University · Brigham and Women's Hospital
Abstract
BACKGROUND: Rotating night shift work disrupts circadian rhythms and has been associated with obesity, metabolic syndrome, and glucose dysregulation. However, its association with type 2 diabetes remains unclear. Therefore, we aimed to evaluate this association in two cohorts of US women. METHODS AND FINDINGS: We followed 69,269 women aged 42-67 in Nurses' Health Study I (NHS I, 1988-2008), and 107,915 women aged 25-42 in NHS II (1989-2007) without diabetes, cardiovascular disease, and cancer at baseline. Participants were asked how long they had worked rotating night shifts (defined as at least three nights/month in addition to days and evenings in that month) at baseline. This information was updated every…
Citation impact
- FWCI
- 38.46
- Percentile
- 100%
- References
- 31
Authors
4Topics & keywords
- Type 2 diabetes
- Shift work
- Medicine
- Cohort study
- Prospective cohort study
- Gerontology
- Diabetes mellitus
- Internal medicine
- Good health and well-being