The International HapMap Project
Baylor College of Medicine · Chinese Academy of Sciences · +46 more institutions
Abstract
The goal of the International HapMap Project is to determine the common patterns of DNA sequence variation in the human genome and to make this information freely available in the public domain. An international consortium is developing a map of these patterns across the genome by determining the genotypes of one million or more sequence variants, their frequencies and the degree of association between them, in DNA samples from populations with ancestry from parts of Africa, Asia and Europe. The HapMap will allow the discovery of sequence variants that affect common disease, will facilitate development of diagnostic tools, and will enhance our ability to choose targets for therapeutic intervention.
Citation impact
- FWCI
- 134.96
- Percentile
- 100%
- References
- 73
Authors
183Topics & keywords
- International HapMap Project
- Human genome
- Sequence (biology)
- DNA sequencing
- 1000 Genomes Project
- Computational biology
- Genome
- Biology
- Partnerships for the goals
Funding
- WMW. M. Keck Foundation
- MUMcGill University
- GCGenome Canada
- WTWellcome Trust
- MOMinistry of Education, Culture, Sports, Science and Technology
- NNNational Natural Science Foundation of China
- UGUniversity Grants Committee
- CAChinese Academy of Sciences
- BNBeijing Normal University
- MOMinistry of Science and Technology of the People's Republic of China
- IAInnovation and Technology Commission
- NINational Institutes of Health
- NINational Institute on Alcohol Abuse and Alcoholism
- NINational Institute on Aging
- NINational Institute of Mental Health
- NINational Institute on Drug Abuse
- NHNational Human Genome Research Institute
- NENational Eye Institute
- NCNational Cancer Institute
- NINational Institute on Deafness and Other Communication Disorders
- NINational Institute of General Medical Sciences
- NINational Institute of Allergy and Infectious Diseases
- NINational Institute of Diabetes and Digestive and Kidney Diseases
- NINational Institute of Neurological Disorders and Stroke
- NINational Institute of Environmental Health Sciences
- NINational Institute of Arthritis and Musculoskeletal and Skin Diseases
- NINational Institute of Biomedical Imaging and Bioengineering
- NINational Institute of Dental and Craniofacial Research
- NCNational Center for Research Resources