Management of bleeding following major trauma: an updated European guideline

Abstract Introduction Evidence-based recommendations are needed to guide the acute management of the bleeding trauma patient, which when implemented may improve patient outcomes. Methods The multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed in 2005 with the aim of developing a guideline for the management of bleeding following severe injury. This document presents an updated version of the guideline published by the group in 2007. Recommendations were formulated using a nominal group process, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) hierarchy of evidence and based on a systematic review of published literature. Results Key changes encompassed in…

• NS
  National Science Foundation
• BS
  Bristol-Myers Squibb
• EL
  Eli Lilly and Company
• P
  Pfizer
• A
  AstraZeneca
• G
  GlaxoSmithKline
• S
  Sanofi
• EL
  Edwards Lifesciences
• BB
  B. Braun Melsungen
• CB
  CSL Behring
• S
  Stryker
• SF
  Swiss Foundation for Anesthesia Research
• SS
  Société Suisse d'Anesthésie et Réanimation
• NI
  National Institute for Health and Care Research
• CO
  College of Emergency Medicine
• SN
  Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
• SG
  Secrétariat Général pour les Affaires Régionales, Etat en Région Aquitaine
• NN
  Novo Nordisk
• AP
  Astellas Pharma
• UZ
  Universität Zürich
• ES
  European Society of Anaesthesiology
• OM
  Olga Mayenfisch Stiftung
• SL
  Swiss Life Stiftung für Chancenreichtum und Zukunft
• ES
  European Society of Intensive Care Medicine
• C
  Cilag