Review of tissue simulating phantoms for optical spectroscopy, imaging and dosimetry

Optical spectroscopy, imaging, and therapy tissue phantoms must have the scattering and absorption properties that are characteristic of human tissues, and over the past few decades, many useful models have been created. In this work, an overview of their composition and properties is outlined, by separating matrix, scattering, and absorbing materials, and discussing the benefits and weaknesses in each category. Matrix materials typically are water, gelatin, agar, polyester or epoxy and polyurethane resin, room-temperature vulcanizing (RTV) silicone, or polyvinyl alcohol gels. The water and hydrogel materials provide a soft medium that is biologically and biochemically compatible with addition of organic…

• MG
  Massachusetts General Hospital
• DC
  Dartmouth College
• TS
  Thayer School of Engineering, Dartmouth College
• NC
  National Cancer Institute

  Award: PO1CA80139