Controlled PEGylation of Monodisperse Fe 3 O 4 Nanoparticles for Reduced Non‐Specific Uptake by Macrophage Cells

A dopamine-PEG based ligand is synthesized and used to stabilize monodisperse 9 nm Fe3O4 nanoparticles in physiological conditions and against non-specific uptake by macrophage cells. Such stable nanoparticles can be used to enhance the efficiency in target-specific drug delivery and to increase the signal-to-noise ratio in magnetic resonance imaging (MRI). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2007/c1975_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the…