Common Sequence Polymorphisms Shaping Genetic Diversity in Arabidopsis thaliana
University of Southern California · Max Planck Society · +6 more institutions
Abstract
The genomes of individuals from the same species vary in sequence as a result of different evolutionary processes. To examine the patterns of, and the forces shaping, sequence variation in Arabidopsis thaliana, we performed high-density array resequencing of 20 diverse strains (accessions). More than 1 million nonredundant single-nucleotide polymorphisms (SNPs) were identified at moderate false discovery rates (FDRs), and approximately 4% of the genome was identified as being highly dissimilar or deleted relative to the reference genome sequence. Patterns of polymorphism are highly nonrandom among gene families, with genes mediating interaction with the biotic environment having exceptional polymorphism…
Citation impact
- FWCI
- 103.53
- Percentile
- 100%
- References
- 35
Authors
18- RMRichard M. Clark
University of Southern California, Max Planck Society, Max Planck Institute for Developmental Biology, Max Planck Institute for Biological Cybernetics, Bernstein Center for Computational Neuroscience Tübingen, Friedrich Miescher Laboratory, University of Tübingen
- GSGabriele SchweikertCorresponding
University of Southern California, Max Planck Society, Max Planck Institute for Developmental Biology, Max Planck Institute for Biological Cybernetics, Bernstein Center for Computational Neuroscience Tübingen, Friedrich Miescher Laboratory, University of Tübingen
- CTChristopher ToomajianCorresponding
University of Southern California, Max Planck Society, Max Planck Institute for Developmental Biology, Max Planck Institute for Biological Cybernetics, Bernstein Center for Computational Neuroscience Tübingen, Friedrich Miescher Laboratory, University of Tübingen
- SOStephan OssowskiCorresponding
University of Southern California, Max Planck Society, Max Planck Institute for Developmental Biology, Max Planck Institute for Biological Cybernetics, Bernstein Center for Computational Neuroscience Tübingen, Friedrich Miescher Laboratory, University of Tübingen
- GZGeorg ZellerCorresponding
University of Southern California, Max Planck Society, Max Planck Institute for Developmental Biology, Max Planck Institute for Biological Cybernetics, Bernstein Center for Computational Neuroscience Tübingen, Friedrich Miescher Laboratory, University of Tübingen
Topics & keywords
- Arabidopsis thaliana
- Sequence (biology)
- Genetics
- Genetic diversity
- Diversity (politics)
- Biology
- Computational biology
- Evolutionary biology
- Life in Land