Combination Antiretroviral Strategies for the Treatment of Pregnant HIV-1–Infected Women and Prevention of Perinatal HIV-1 Transmission

Eunice Kennedy Shriver National Institute of Child Health and Human Development · University of Illinois Chicago, Rockford campus · +9 more institutions

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Abstract

Objective

To evaluate the impact of different antiretroviral regimens on perinatal HIV-1 transmission at the population level.

Design

Prospective cohort study. Plasma HIV-1 RNA levels were serially measured in 1542 HIV-1-infected women with singleton live births between January 1990 and June 2000. MAIN OUTCOME MEASURE: HIV-1 status of the infant.

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