reviewScienceApr 2, 2015GREEN OA

Cancer and the microbiota

WSWendy S. Garrett

Broad Institute · Harvard University · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

A host's microbiota may increase, diminish, or have no effect at all on cancer susceptibility. Assigning causal roles in cancer to specific microbes and microbiotas, unraveling host-microbiota interactions with environmental factors in carcinogenesis, and exploiting such knowledge for cancer diagnosis and treatment are areas of intensive interest. This Review considers how microbes and the microbiota may amplify or mitigate carcinogenesis, responsiveness to cancer therapeutics, and cancer-associated complications.

Citation impact

1,335
total citations
FWCI
35.23
Percentile
100%
References
119
Citations per year

Authors

1

Topics & keywords

Topics
Keywords
  • Carcinogenesis
  • Cancer
  • Biology
  • Host (biology)
  • Gut flora
  • Host factors
  • Bioinformatics
  • Computational biology
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