articlePLoS ONEJul 3, 2014GOLD OA

Evaluating the Quality of Evidence from a Network Meta-Analysis

University of Ioannina · University of Modena and Reggio Emilia · +2 more institutions

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Abstract

Systematic reviews that collate data about the relative effects of multiple interventions via network meta-analysis are highly informative for decision-making purposes. A network meta-analysis provides two types of findings for a specific outcome: the relative treatment effect for all pairwise comparisons, and a ranking of the treatments. It is important to consider the confidence with which these two types of results can enable clinicians, policy makers and patients to make informed decisions. We propose an approach to determining confidence in the output of a network meta-analysis. Our proposed approach is based on methodology developed by the Grading of Recommendations Assessment, Development and Evaluation…

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1,398
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Authors

5

Topics & keywords

Keywords
  • Meta-analysis
  • Pairwise comparison
  • Computer science
  • Network analysis
  • Ranking (information retrieval)
  • Systematic review
  • Quality of evidence
  • Grading (engineering)
UN Sustainable Development Goals
  • Peace, Justice and strong institutions
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