articleJournal of Bone and Mineral ResearchFeb 5, 2008BRONZE OA

Frequency and Risk Factors Associated With Osteonecrosis of the Jaw in Cancer Patients Treated With Intravenous Bisphosphonates

The University of Texas MD Anderson Cancer Center · Novartis (Switzerland)

PubMed
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Abstract

Introduction

Osteonecrosis of the jaw (ONJ) has been reported in patients treated with bisphosphonates. The incidence and risk factors associated with this disorder have not been clearly defined.

Materials And Methods

We conducted a retrospective analysis of 4019 patients treated with intravenous bisphosphonates between 1996 and 2004. Our goals were to estimate the frequency, understand the clinical presentation, and identify risk factors associated with ONJ development.

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Funding