Characterization of the Oral Fungal Microbiome (Mycobiome) in Healthy Individuals
University Hospitals Case Medical Center · Case Western Reserve University · +1 more institution
Abstract
The oral microbiome-organisms residing in the oral cavity and their collective genome-are critical components of health and disease. The fungal component of the oral microbiota has not been characterized. In this study, we used a novel multitag pyrosequencing approach to characterize fungi present in the oral cavity of 20 healthy individuals, using the pan-fungal internal transcribed spacer (ITS) primers. Our results revealed the "basal" oral mycobiome profile of the enrolled individuals, and showed that across all the samples studied, the oral cavity contained 74 culturable and 11 non-culturable fungal genera. Among these genera, 39 were present in only one person, 16 genera were present in two participants,…
Citation impact
- FWCI
- 32.44
- Percentile
- 100%
- References
- 41
Authors
7- MAMahmoud A. GhannoumCorresponding
University Hospitals Case Medical Center
- RJRichard J. Jurevic
Case Western Reserve University
- PKPranab K. Mukherjee
Case Western Reserve University, University Hospitals Case Medical Center
- FCFan Cui
Case Western Reserve University, University Hospitals Case Medical Center
- MSMasoumeh Sikaroodi
George Mason University
Topics & keywords
- Cladosporium
- Biology
- Internal transcribed spacer
- Microbiome
- Fusarium
- Oral Microbiome
- Microbiology
- Aspergillus