SERS—a single-molecule and nanoscale tool for bioanalytics
Federal Institute For Materials Research and Testing · Phipps Houses · +4 more institutions
Abstract
Surface enhanced Raman scattering (SERS) at extremely high enhancement level turns the weak inelastic scattering effect of photons on vibrational quantum states into a structurally sensitive single-molecule and nanoscale probe. The effect opens up exciting opportunities for applications of vibrational spectroscopy in biology. The concept of SERS can be extended to two-photon excitation by exploiting surface enhanced hyper-Raman scattering (SEHRS). This critical review introduces the physics behind single-molecule SERS and discusses the capabilities of the effect in bioanalytics (100 references).
Citation impact
- FWCI
- 18.15
- Percentile
- 100%
- References
- 92
Authors
3- JKJanina KneippCorresponding
Federal Institute For Materials Research and Testing, Phipps Houses, Harvard University
- HKHarald Kneipp
Boston University, Harvard University
- KKKatrin Kneipp
Boston University, Harvard–MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Harvard University
Topics & keywords
- Raman scattering
- Nanoscopic scale
- Photon
- Molecule
- Excitation
- Raman spectroscopy
- Scattering
- Nanotechnology