Meta-analyses of cognitive functioning in euthymic bipolar patients and their first-degree relatives
Maastricht University · European Graduate School of Neuroscience
Abstract
Previous work suggests that impairments in executive function and verbal memory in particular may persist in euthymic bipolar patients and serve as an indicator of genetic risk (endophenotype). METHOD: A systematic review of the literature was undertaken. Effects sizes were extracted from selected papers and pooled using meta-analytical techniques.
In bipolar patients, large effect sizes (d>0.8) were noted for executive functions (working memory, executive control, fluency) and verbal memory. Medium effect sizes (0.5
Citation impact
- FWCI
- 15.52
- Percentile
- 100%
- References
- 92
Authors
4- BABaer ArtsCorresponding
Maastricht University, European Graduate School of Neuroscience
- NJNienke Jabben
Maastricht University, European Graduate School of Neuroscience
- LKLydia Krabbendam
Maastricht University, European Graduate School of Neuroscience
- JVJim van Os
Maastricht University, European Graduate School of Neuroscience
Topics & keywords
- Bipolar disorder
- First-degree relatives
- Psychology
- Cognition
- Degree (music)
- Clinical psychology
- Psychiatry
- Medicine
- Quality Education